Blood Creatinine Level & Dialysis

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Creatinine is the most reliable indicator showing the kidney is functioning properly. The kidney will maintain the blood creatinine in the normal range when functioning properly.

In case the creatinine level is high it signifies impaired kidney function or disease.

In case the kidney is not performing properly for any reason, it is for this purpose, standard blood tests routinely check the amount of creatinine in the blood. Extremely high levels of creatinine in the blood signify the problem related to the kidney.    The clearance of creatinine can be measured in two ways. It can be calculated based on a formula using serum (blood) creatinine level, patient’s weight, and age.  Creatinine clearance can be measured directly as well. It is done by collecting a 24-hour urine sample and then drawing the blood sample. After this, the level of creatinine, in both urine and blood is taken for comparison.

  • In the case of normal creatinine clearance for healthy women, it should be 88-128 mL/min. While in the case of males it should be 97 to 137 mL/min (In general the levels may vary slightly).
  • Blood urea nitrogen (BUN) level is also a determining factor helping to know how your kidney functions. Urea is also a metabolic byproduct. This can build up in case kidney function is impaired.
  • The BUN-to-creatinine ratio usually gives information with high accuracy about kidney functioning and its possible underlying cause compared with creatinine level alone.  An increase in dehydration may be witnessed due to increased BUN.

Recently study found elevated creatinine levels in infants. It was associated with bacteremia. On the other hand in adult males, it has been linked to an increased risk of prostate cancer.

  • Chronic Kidney Disease Symptom
  • High Creatinine Level
  • Early signs showing kidney stones include high blood pressure. It doesn’t show any symptoms. People may have the issue but don’t get to know about it because they do not feel sick.

A person’s glomerular filtration rate (GFR) is used for measuring how well the kidney is filtering wastes through the blood. GFR is calculated from a routine measurement of creatinine in the blood. The result is termed as estimated GFR (eGFR). Creatinine is a waste product. It is formed by the normal breakdown of muscle cells. Healthy kidneys extract creatinine from the blood and put it back into the urine to leave the body. In case the kidney is not performing well, creatinine will be building up in the blood.

What are normal blood creatinine levels?

In a normal scenario, the levels of creatinine in the blood are usually 0.6 to 1.2 milligrams (mg) per deciliter (dL) in males. On the other hand, it is 0.5 to 1.1 milligrams per deciliter in adult females.

What is the issue considered due to high creatinine levels?

A person having a single kidney may have a normal level of about 1.8 or 1.9. In case Creatinine level increases 2.0 or more in babies and 5.0 or more in adults severe kidney issue is signified from it. There is a need for a dialysis machine to remove wastes from the blood. It is based upon several considerations including the BUN, creatinine level, potassium level, and amount of fluid which the patient is retaining.

What is the cause of high creatinine levels in the blood?

Any condition impairing the function of the kidneys is most likely to raise the level of creatinine in the blood. It is important for recognizing if the process which leads to kidney dysfunction (kidney failure, azotemia) longstanding or recent. Recent elevations can be even more easily treated.

The most common causes of serious kidney disease in adults

  • High Blood Pressure and
  • Other Causes Of Elevated Blood Creatinine Levels Include:
  • Drugs (for example, cimetidine [Bactrim]) cause abnormally elevated creatinine levels.

Serum creatinine can also spike increase after ingestion of a large amount of dietary meat. Hence, nutrition can sometimes play an important role in creatinine measurement. Kidney infections, rhabdomyolysis (abnormal muscle breakdown), and urinary tract obstruction may also lead to an increase in creatinine levels.   

Who has low or high blood creatinine levels?

Muscular young or middle-aged adults can also have creatinine in the blood. Elderly persons might have less creatinine in the blood than normal people. Infants have normal levels of nearly 0.2 or more, based on muscle growth.

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